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Science
13 August 2024

Climate Change Fuels Disease Threats And Solutions

Experts reveal rising infectious disease risks linked to climate change as biotechnology offers new hope.

Climate change is affecting various aspects of life, and one particularly alarming area is its impact on infectious diseases. Researchers are sounding the alarm, emphasizing the heightened risk as climate conditions shift.

According to infectious disease expert Jan Semenza, climate change is becoming one of the leading drivers behind the emergence of infectious diseases. During his work at the European Center for Disease Prevention and Control, he noted how environment and globalization accounted for over 60% of these emerging threats.

This complex interplay between climate change and health risks can be observed through growing numbers of pathogens making their way across borders due to shifting weather patterns. For example, as the planet warms, we see changes in animal migration and insect behaviors, which could facilitate cross-species transmission of viruses.

Researchers have raised concerns about various viruses' potential to infect humans, with projections estimating around 10,000 viral species circulating among wildlife. Alarmingly, recent assessments predict climate and land use changes could pave the way for 4,000 cross-species viral transmissions by 2070.

The primary culprit behind this shift is thought to be human encroachment on wildlife habitats. When we share spaces, spillover events may arise, igniting new outbreaks of disease.

Take the Asian tiger mosquito, for example. These pesky carriers of significant diseases like dengue and Zika have expanded their geographical reach northward each year, now finding homes even as temperatures dip.

Joacim Rocklöv, another leading researcher, highlighted the troubling adaptation capabilities of these invasive species. His observations suggested these mosquitoes may no longer hibernate, which could allow them to transmit pathogens throughout the winter months.

But it's not all doom and gloom, as researchers are hard at work developing innovative technologies to combat these challenges. For example, genomic pathogen surveillance, artificial intelligence applications, and new disease control measures are being tested to mitigate risks effectively.

One such approach involves the Wolbachia method, which seeks to infect mosquitoes like Aedes aegypti with bacteria to halt their disease-carrying capabilities. This method represents hope for tackling diseases caused by these vectors.

Meanwhile, the biotechnology sector is tapping critical potential using microorganisms for environmental remediation. Specifically, new digital technologies are being explored to help bioengineer solutions to pollution and waste management.

Michael O'Donohue, leading the Bioindustry 4.0 project, explained the historical context of biotechnology's evolution. From centuries-old practices of brewing to produce beer and antibiotics, biotechnology is now positioning itself as key to sustainable production methods.

Utilizing microbes like yeasts and fungi at mild temperatures boosts the potential for cleaner industrial processes. Unlike traditional chemical methods, which often rely on hazardous materials, biotechnology thrives under conditions safe for health and the environment.

Although promising, the application of these biological processes has been capped by inconsistent behaviors of microorganisms. O'Donohue underscores the importance of harmonizing biotechnology with digital technology to optimize industrial reliability.

To do this, researchers aim to implement real-time sensors within bioreactors, allowing for the continuous monitoring of microbial health and production efficiency. This integration ensures more controlled and reproducible results, critical for industrial applications.

Despite facing challenges, the European biotechnology sector holds immense potential, with the industry valued at around €720 billion and growing. Efforts are underway to strengthen its positioning against international competitors, especially the US.

O'Donohue pointed out the US's dominance, capturing nearly 60% of the global biotech market share. He believes Europe must embrace its historical roots, leveraging existing infrastructure and expertise to revitalize its biotech industry.

Beyond boosting market competition, the European Commission has outlined initiatives to integrate regulatory frameworks for biotech innovation. These measures aim to streamline regulations and support innovators on their entrepreneurial journeys.

To complement these efforts, the proposed EU Biotech Hub seeks to create pathways for businesses to navigate the extensive models of regulation and support. O'Donohue highlights the significance of guiding European science to stay abreast of global changes.

Young companies like Calidris Bio are already tapping these advancements to improve sustainability practices. Their objective is clear: to create high-quality protein replacements for unsustainable fishmeal and soy products.

Still, the work isn't over; rigorous testing for safety, taste, and nutritional value must accompany innovations. Calidris Bio's co-founder Lieve Hoflack expressed gratitude for assistance offered through initiatives like IBISBA, which bridges research gaps and connects budding innovators with resources.

Overall, the convergence of biotechnology and climate-conscious initiatives holds significant promise for the future. By addressing environmental concerns through sustainable practices, scientists can hope to mitigate the impact of both climate change and infectious disease spread.

Innovations will prove desperately needed as challenges mount and public health perspectives continually evolve. The intersection of climate, science, and technology offers critical solutions to tackle our ever-changing world.

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