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Science
27 July 2024

Chilean Yeast Strains Promise New Lager Beer Flavors

Scientists explore diverse yeast hybrids from Patagonia for fresh brewing potential

In a groundbreaking twist for beer enthusiasts and brewers, scientists in Chile have tapped into the rich biodiversity of Patagonia to develop new hybrid yeast strains that promise to revolutionize lager beer flavors. For ages, brewing has relied on a narrow genetic pool, leading to a scarcity of distinctive tastes among lagers. Most of these intellectual brews stem from a single yeast strain that was fortuitously born around 1600. However, by harnessing the untamed nature of Chile's natively found yeasts, researchers are paving the way for unprecedented aromas and flavors that could soon hit pubs worldwide.

Lager beer is remarkably popular—spanning brands like Budweiser, Corona, and Heineken. Alternatively, lager and ale are the two main beer types, distinctly defined by their fermentation temperatures, with lagers brewed at cooler temperatures resulting in a crisper taste, and ales fermenting in warmer conditions to develop their characteristic spiciness. Central to both types of beer is the action of yeast, small fungi that transform sugars into alcohol and carbon dioxide, producing the effervescent beverages many enjoy today.

Francisco Cubillos, the principal investigator of the study and a professor at the University of Santiago, remarked, "All the lager beers that we drink now come from a single event from a yeast generated 500 years ago." With only 86 commercial strains of lager yeast available, the urgency to diversify flavor profiles led to the exploration of the unique varieties found in Patagonia. Cubillos is driven by the enthusiasm of finding new flavors, aiming to break the molds of the existing palate with hybrids that promise to invigorate the beer market.

The genesis of the hybrid lager yeast stems from the humble brew process before modern technology. Traditionally, the first lager yeast, known scientifically as Saccharomyces pastorianus, was born out of a chance interaction between two other strains, Saccharomyces cerevisiae and Saccharomyces eubayanus, in Bavaria. This hybridization incident sparked a brewing lineage that has largely stagnated over centuries. With the advent of these Chilean hybrids, scientists have begun to look again at the viability of enhancing lager with a fresher taste.

In the recent study published in PLOS Genetics, researchers described their iterative experimentations with hybrid yeasts derived from tree bark samples in Patagonia. These strains were found to produce unique aromas compared to commercial varieties, with some hybrids yielding sweet notes, while others channeled spiciness reminiscent of cloves. As natural explorers of flavor, the researchers initially struggled with early hybrids that failed to fully ferment the sugars present, leading to the obvious frustration in the lab.

However, through a method known as experimental evolution, they placed these lackluster yeasts in fresh sugar-laden test tubes to observe how their traits would develop over generations, eventually leading to vibrant yeast strains capable of producing enticing lagers characterized by their distinct flavors. Over seven months and 250 iterations, the yeasts thrived, evolving into robust hybrid strains.

Jennifer Molinet, the study's first author, joyfully recalled the moment of success: "I was so happy, and I was jumping around the lab." With all the sugar now being consumed, the yeasts started unveiling new aromatic profiles. The complexity brought forth by these new hybrids captures the hopes for transforming lagers into flavor-packed contenders, marking a significant step in brewing history.

Reactions to the findings have been positive. Zach Lilla, head chemist at Advanced Analytical Research Lab, highlighted the promise of the research. Still, discussions among brewing experts assert that these hybrids' success must translate from the lab to real brewing environments—a critical next step for the researchers. Christopher Curtin, an associate professor of fermentation microbiology, provides insight into the potential challenges that lie ahead in scaling up production, notably urging for thorough sensory analyses to ensure that the beer holds up to consumer preferences.

The science doesn't stop there. Researchers have not only created hybrid yeasts but have also begun dissecting their genetic characteristics, primarily focusing on their mitochondria. These cellular structures dictate metabolic qualities and fermentation efficiency. The ability to know which genetic features yield the best-performing yeast is advantageous for future brewing endeavors. Cubillos has optimistically stated, "We need to catch up with 500 years of domestication... But we see it as an opportunity." Through careful selection and experimentation, a new realm of lager brewing could emerge, paving the path for innovative flavors long overdue in the market.

With the evidence of success in breeding new yeast strains, lagers that encompass diverse potencies could soon line pub shelves, offering beer lovers a taste of the novel and reducing the conformity so prevalent in the current brewing world. For a beer enthusiast, this could mean anything from a spicy, clove-infused lager to an unexpectedly sweet-crisp lager, resulting from the natural brilliance found in Chile’s forests. As the researchers put forth their hybrids for more extensive trials, beer aficionados are left on the edge of anticipation—ready for the next wave of flavors that may soon redefine their beloved beverage.

While the brewing industry remains heavily reliant on a few dominant strains, the potential introduction of these Patagonian hybrids brings a fresh breeze of creativity. The story serves as a reminder of the endless possibilities that come from exploring nature's offerings, opening doors to flavors that tradition alone has yet to realize. This innovative journey could not only reinvigorate the lager genre but also redefine how we perceive the interplay between nature and food as we savor our next pint.

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