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04 March 2025

Weight Loss Medications: Impact On Intimacy And Vision Risks

Experts discuss the effects of drugs like Ozempic on relationships and potential eye conditions.

Recent trends surrounding anti-diabetic medications, particularly semaglutide marketed under the brand name Ozempic, have sparked discussions not just about weight loss, but also about intimate relationships and eye health. While these medications are praised for helping individuals manage obesity and type 2 diabetes, experts warn of potential adverse effects on both intimacy and eyesight.

Dr. Vyankatesh Shivane, a consultant diabetologist and metabolic physician at Jaslok Hospital and Research Centre, Mumbai, points out the intertwined relationship between weight loss and increased self-confidence. He states, "A reduction in weight increases self-confidence, which makes both partners more interested in sex, improving sexual desire." This sentiment resonates strongly, as many users report enhanced self-esteem and energy levels leading to more fulfilling intimate moments.

Yet, the picture is not entirely rosy. While weight loss is typically linked to enhanced intimacy, Dr. Shivane highlights troubling evidence surrounding GLP-1 receptor agonists like Ozempic and Mounjaro (tirzepatide). Some studies indicate these drugs might reduce sexual desire for certain individuals. He emphasizes, "This area requires more research to determine whether these drugs, aside from controlling diabetes and inducing weight loss, also affect sexual dysfunction."

Adding to this complexity, Dr. Madhulika Singh, senior consultant obstetrician and gynaecologist, explores the varied impacts of different weight loss medications. She mentions, "Some medications prescribed for weight loss, like appetite suppressants, can cause severe side effects like fatigue, mood swings, and decreased libido." This comment raises concerns as it notes how these side effects can dampen intimacy and, conversely, prompt couples to avoid sexual encounters.

Dr. Singh stresses not just the psychological effects but the physical side effects, such as nausea and digestive issues, experienced by some patients taking drugs like Ozempic or Wegovy. She notes, "These symptoms can lead patients to feel less confident or comfortable during intimate moments," drastically affecting their relationships.

Another significant aspect explored by the experts is the hormonal consequences of these medications. Dr. Singh suggests, "Some weight loss drugs may lower testosterone levels in men or impact women's hormonal balance." This connection highlights the need for comprehensive discussions between patients and healthcare providers about the potential side effects before beginning any medication regimen.

Meanwhile, the concerns do not end with intimacy. A major study from Johns Hopkins University raised troubling associations between semaglutide and the risk of developing non-arteritic ischemic anterior optic neuropathy (NAION), sometimes referred to as 'eye stroke.' This condition, which can lead to sudden vision loss, typically affects one eye. The study tracked over 37 million people, evidencing the medication's link to increased vulnerability to this rare but severe eye condition. Researchers warned about the potential risk posed by semaglutide, calling it attention from healthcare professionals. "We observed an increased NAION risk with semaglutide exposure relative to non-exposure," highlighted the researchers, indicating the serious repercussions these medications might carry.

While NAION affects approximately one in 10,000 individuals, researchers reiterated the need for heightened awareness among prescribing clinicians. The urgency of their message lies not only within the immediate health concerns but also calls for thorough evaluations of the drugs being offered to patients. The researchers argued, "We urge clinicians to weigh the concern for increased risk of this rare but potentially blinding eye condition with the many therapeutic benefits of semaglutide," demonstrating the balance medical professionals must navigate.

Despite these serious insights, millions continue to use weight loss drugs like Ozempic, with around half a million users in the UK and about 15 million people across the US. Many are pursuing significant weight reduction—often up to 20% within just a few months—resulting in improved health outcomes for cardiovascular issues, enriched lifespan, and enhanced quality of life for some.

Yet, ensuring patient safety involves more than just prescribing medications. Patients are urged to communicate openly with their doctors about any changes they experience upon beginning treatment. This is especially true if individuals notice adverse effects on their intimacy, growing relationships as Dr. Singh advises, "If you’re noticing any negative impacts on your intimacy due to weight loss drugs, you should talk to your doctor.”

Addressing underlying health issues, such as uncontrolled diabetes or hormonal imbalances, can also lead to improved intimacy. Dr. Shivane noted, "When the underlying causes are treated—either through improved blood sugar control or hormonal treatments for hypogonadism—both males and females experience increased libido and enhancement of intimacy." This perspective emphasizes not only the immediacy of managing one’s weight but also the complexity behind maintaining intimacy with partners.

Clearly, the dynamics of weight loss drugs like Ozempic intertwine with various aspects of health, and continual research is necessary to fully understand their sweeping effects—positive and negative—on users' lives, especially concerning intimacy and eye health.