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Science
28 February 2025

Unique Glass-Like Preservation Of Human Brain Found At Herculaneum

Researchers reveal remarkable insights from the 79 CE Vesuvius eruption, showcasing the effects of extreme heat on organic matter.

Researchers have made a groundbreaking discovery at the archaeological site of Herculaneum, Italy, where unique glass-like remains of human brain tissue have been found preserved within the skull of a young male victim of the catastrophic eruption of Mount Vesuvius in 79 CE. This remarkable finding sheds light on the effects of extreme heat on organic materials and presents unprecedented insights within the fields of material science and archaeology.

The eruption of Vesuvius on 24 August 79 CE resulted in tragic consequences for the towns of Herculaneum and Pompeii, claiming thousands of lives due to the violent pyroclastic flows and ash clouds. Archeological excavations have uncovered around 2,000 bodies from the sites. Among these, only the vitrified remains of the brain identified from the guardian of the Collegium Augustalium stand out as the sole occurrence of organic glass formation from human tissue documented to date.

Scientists, including lead researchers Giordano G., Pensa A., and Vona A. from the University of Roma Tre, conducted extensive analyses of this find using advanced techniques such as Scanning Electron Microscopy (SEM), Differential Scanning Calorimetry (DSC), and Raman spectroscopy. These methods allowed them to determine the unique properties and origin of the glassy material. The preservation of the brain tissue is attributed to rapid cooling from very high temperatures—well above 510 °C—exposure during the eruption. The research team hypothesized the brain remained intact long enough to undergo vitrification and then was rapidly cooled by volcanic activity.

"This unique finding belongs to a victim of the eruption found lying in his bed inside the Collegium Augustalium," noted the authors of the article. The chemical composition analysis revealed the presence of proteins typical of human brain tissue, along with fatty acids from human adipose tissues, supporting the identification of the remains as organic. The glassy appearance, described as black and shiny akin to obsidian, suggests structural preservation of the brain's neural features, which includes complex networks of neurons and axons.

During the study, notable thermal transitions identified through DSC indicated the reactions typical of vitrification, showcasing the glass transition temperature at which the brain transformed from organic material to glass. Raman spectroscopy enhancements displayed increasing structural order within this carbonaceous component as temperatures rose—a clear indicator of chemically altered conditions leading to the extraordinary preservation state. The research concluded with compelling evidence: the brain sample is composed of organic glass formed at extremely high temperatures, marking this as the first known incident of its kind.

The discovery of glass-like brain remains opens up significant inquiries within related scientific domains about the influence of high-temperature conditions on organic matter, which has historically only been observed through dehydration or saponification. "Our comprehensive characterization shows compelling evidence of human brain remains composed of organic glass formed at high temperatures," asserted the article's authors.

This finding has remarkable implications beyond archaeology; it significantly informs our comprehension of material properties under thermal stress, providing insights relevant to forensic biology and future research on preservation techniques across various contexts, including natural phenomena and anthropological studies. Despite existing knowledge on brain preservation mechanisms, the phenomenon of vitrification at such high temperatures has not been documented adjacent to human tissue.

Given the necessity of very specific conditions for glass formation and preservation indicated by this research, practical applications of these insights may extend to innovative approaches for preserving organic materials in both archaeological contexts and modern biomedical applications.

To summarize, the brain tissue examined from Herculaneum exemplifies the unique preservation of organic glass as influenced by extreme thermal events, providing insightful perspectives on both past human experiences and future preservation methodologies. This exceptional case also raises broader questions about human resilience and vulnerability under extraordinary natural disasters.