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Health
09 November 2024

Spotting Early Symptoms Of Dementia Can Save Lives

Awareness of key indicators and new breakthroughs can lead to timely care and treatment for affected individuals

Detecting the early signs of dementia can be tricky, especially since many symptoms often get overlooked. This is increasingly important as studies show more people are affected by cognitive impairments than previously realized. A recent study sheds light on the reality of cognitive impairments among older adults, emphasizing the need to recognize early symptoms.

Between memory loss and confusion, it’s easy to mistake some behaviors for normal aging—until they aren’t. Dementia is not just one specific disease but rather encompasses several conditions, with Alzheimer's disease being the most prevalent. Other types include vascular dementia and Lewy body dementia. While we often associate dementia with older adults, particularly those over sixty-five, the fact is it can strike anyone, regardless of age.

Statistics depict the sobering reality: approximately 944,000 people across the UK live with dementia, and projections indicate this figure will climb to over 1 million by 2030. Indeed, one out of every eleven individuals over sixty-five is grappling with dementia. What does this mean for families and caregivers? Well, spotting the early warning signs can be key to managing and treating this condition effectively.

Two prominent symptoms often cited are restlessness and wandering. These may manifest as loved ones aimlessly moving around the house or, more alarmingly, leaving home unexpectedly, sometimes at odd hours. Yet, memory loss tends to garner the lion's share of attention when it came to warning signs. Other primary symptoms can include challenges with tasks requiring concentration and planning, noticeable changes to mood or personality, and difficulties in communication, like finding the right words during conversations.

Investigative efforts involving recent breakthroughs indicate hope on the horizon. Exciting developments have been made with two new drugs aimed at altering the decline associated with Alzheimer’s. Dr. Richard Oakley, the associate director at the Alzheimer's Society, hinted at the advent of these medications, proclaiming, “After 20 years with no new Alzheimer's disease drugs in the UK, we now have two potential new drugs.” This could signal what he describes as the “beginning of the end for Alzheimer’s disease.”

Interestingly, the maligned proteins tau and amyloid, often linked to catastrophic symptoms of Alzheimer's, are under scrutiny as researchers explore their interactions more deeply, hoping they could be dismantled by these new therapies. One drug, lecanemab, has shown promising signs by slowing symptom progression by 27% due to its ability to prevent the formation of amyloid plaques, giving rise to hopes for others targeting both tau and amyloid.

Meanwhile, scientists propose another potential early warning sign may be loss of smell. New research finds individuals bearing the ApoE e4 gene—a gene increasing Alzheimer's risk—are less likely to possess strong olfactory senses. Between the ages of 65 and 69, carriers begin exhibiting diminished abilities to detect odors, raising speculation about how olfactory assessment could become integral to predicting cognitive decline later.

Dr. Matthew GoodSmith from the University of Chicago shared insightful observations on this groundbreaking research: “Testing a person's ability to detect odors may be useful for predicting communication issues.” While findings are still in their infancy and require more research, they pave the path for identifying individuals at risk early, enabling them to seek timely interventions.

Highlighting another dimension to this issue is the alarming prevalence of undiagnosed cognitive impairments, particularly within vulnerable populations. A study conducted by the Regenstrief Institute explored the occurrence of cognitive impairment among patients at Federally Qualified Health Centers—facilities serving millions of patients, regardless of income or insurance—and revealed staggering statistics. More than half of the 204 older adults studied were African American, and the results were disquieting: about 82 percent faced unrecognized dementia or mild cognitive impairment. This was more than double the figures for White patients. Only 26 percent of the study group enjoyed sound cognitive health.

Such lack of diagnosis can have severe ramifications, leading to poor health outcomes and limiting access to necessary resources for treatment. Malaz Boustani, M.D., senior author of the study, emphasizes, “Delaying diagnosis leads to poor health outcomes for patients and their care partners.” To combat these inequalities, the study recommends scalable and culturally sensitive strategies to facilitate early detection of cognitive impairments.

The stakes are high—earlier diagnosis can grant affected individuals access to new therapies and support systems, significantly influencing their quality of life. Some of these therapies promise to modify the course of cognitive decline, like the new amyloid-lowering treatments, which might help bolster cognitive abilities. The importance of this early and equitable detection cannot be overstated, especially for low-income communities where resources can be sparse.

Machine learning presents another fascinating avenue of exploration. Researchers are leveraging technology to sift through electronic health records, aiming for quicker, cost-effective methods to detect cognitive impairments efficiently. The aim is to create predictive tools for those at risk, addressing diagnosis concerns with remarkable urgency, particularly for older adults who frequently face barriers to healthcare.

Understanding the underlying reasons for discrepancies related to diagnosis becomes imperative. Researchers assert the need for intervention—not just by improving detection methods but by also tackling stigma surrounding cognitive impairments. Addressing fears tied to independence plays heavily on older adults' reluctance to bring up cognitive health with healthcare providers.

The study divulging the alarming rates of undiagnosed cognitive impairments—published recently—offers much food for thought. What’s needed now is proactive approach to engage families, communities, and healthcare systems to prioritize brain health and empower older adults to seek assistance. The power of early detection, early treatment, and education can significantly change the tide against dementia and cognitive impairments. We owe it to ourselves and our loved ones to remain vigilant and informed, ensuring we act early when the signs become apparent.

To sum it up, awareness is key. The ability to spot subtle changes, support loved ones verbalizing their concerns about cognitive health, and advocating for thorough check-ups can be monumental. While science steadily progresses toward treatment breakthroughs, patients themselves and their advocates must remain the first line of defense. After all, being prepared can make all the difference.