On a recent episode of The Tonight Show Starring Jimmy Fallon, comedienne Nikki Glaser shared her candid thoughts about the increasing use of Ozempic as a weight-loss solution, sparking a fresh debate on societal attitudes toward body image and the medication itself. With her characteristic humor and insight, Glaser not only expressed her support for those opting for the drug but also challenged the stigma associated with it, advocating for a more open dialogue.
Glaser’s remarks came just days after her appearance at the 25th Annual Mark Twain Prize for American Humor, where she showcased her dynamic personality. During the show, she exclaimed, “Oh, I love it, I love. I’m like, do it, do it. I have no judgment. If you want to do Ozempic, hell yeah, girl. I want people to feel more comfortable talking about doing it, because I feel like there’s, like, this shame—and the shame is only from thin people who want you to stay fat. Like that's really where it's coming from.” The comedienne characterized the backlash toward Ozempic users as rooted in jealousy, questioning, “They are so mad that you’re getting thin now, because that’s all they have, right?”
Glaser's comments are striking amidst the broader controversy regarding the prescription drug, which is primarily used in managing type 2 diabetes but has gained notoriety as a favored weight-loss remedy among celebrities and influencers alike. Critics of Ozempic often express concern for individuals with diabetes, claiming that weight-loss seekers are usurping medication intended for those in need. Glaser dismissed these allegations, pointing out, “They just go, ‘You’re stealing medicine from diabetics who need it.’ Like anyone’s ever cared about someone with diabetes who doesn’t have it.” She added that resentful voices are often “thin white women” who seem to prioritize their beauty standards over health considerations.
These sentiments were echoed in the discussions surrounding acclaimed actress Kathy Bates, who recently shared her health journey lighting the spotlight on the connection between personal struggle and public perception. Bates, 76, disclosed in October 2024 that she lost approximately 20 pounds thanks to Ozempic, alongside an impressive 80 pounds overall through lifestyle changes made over the past seven years. The Misery star, diagnosed with type 2 diabetes around 2017, explained her weight loss journey to People, stating, “It’s very hard to say you’ve had enough.” Bates admitted that her eating habits had often been driven by emotional distress, and she revealed, “I ate because I was afraid, and I ate because it was a FU to my self-esteem.”
Despite ongoing controversies, Glaser remains a prominent advocate for candid conversations about weight loss. She pointed out that the perception of those using Ozempic is often shaped by misunderstandings and pop culture narratives. The discussion continued as she noted, “I think you’re upset that Kathy Bates has a thigh gap. That’s more what it could be about, I think.” The actress was praised for sharing her struggles publicly, which Glaser believes reflects a broader issue within our society—one that often vilifies individuals for pursuing their health and wellness goals, regardless of the methods they choose.
Celebrity endorsements of Ozempic are growing, with many public figures like Amy Schumer, Oprah Winfrey, and Sharon Osbourne also acknowledging their usage. Glaser humorously remarked on the side effects of the drug during her podcast appearance on Grindr Presents: Who’s The A—–? with Katya, highlighting the real experiences of those who opt for the medication: “Let’s just say the trips to the bathroom would say otherwise, okay? We know if you’re on it because you’re s–tting your pants,” she joked, reinforcing her stance on accepting diverse approaches to weight management.
Amidst various pop culture discussions surrounding body image, weight loss medications, and public perception, Glaser's remarks seek to provide a counterpoint to prevailing criticisms, emphasizing compassion and understanding rather than judgment. As she prepares to host the 2026 Golden Globes, her voice continues to resonate in a conversation that is both urgent and nuanced, encouraging people to engage in dialogues about body positivity and the choices individuals make in their health journeys.