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Science
27 January 2025

Netrin-1 Revealed As Key Factor For Cancer Prognosis And Immune Response

A comprehensive pan-cancer analysis highlights NTN1's potential as both prognostic biomarker and immune infiltration risk factor, particularly for skin cutaneous melanoma.

Comprehensive analysis identifies Netrin-1 as a significant risk factor for immune infiltration and prognosis across multiple cancers, particularly skin cutaneous melanoma (SKCM).

Recent research led by various scientists has delved deeply... across numerous tumor types.

This study conducted extensive investigations... advising the potential clinical utility of NTN1.

The utility of Netrin-1 extends beyond initial mechanisms... spanning detailed analyses of gene expressions and immune interactions.

NTN1 plays a multifaceted role... presenting significant clinical applications.

Notably, NTN1 has been heavily implicated... showcasing the complexity of immune responses and tumor interactions.

By analyzing data sets... researchers have unveiled NTN1’s strong correlations with immune cell infiltration.

Integrated approaches utilizing machine learning... provide insights pointing to NTN1’s varied behavior across cancer types.

This analysis is also reinforced by findings from TCGA,... concluding NTN1 exhibits both prognostic and therapeutic potential.

With continued investigations, NTN1's dual role may lead to new cancer treatment strategies...