Luxembourg's Prince Frederik Passed Away at 22 After Long Battle With Rare Disease
Tragic loss marks end of his inspiring fight against PolG disease.
Luxembourg's Prince Frederik, the son of Prince Robert of Luxembourg and nephew of Grand Duke Henri, died on March 1, 2025, in Paris at the tender age of 22. His family confirmed the sad news via the website of the PolG Foundation, which the young prince had established to raise awareness about the rare and debilitating disease known as PolG.
Born with the condition, Frederik had dedicated much of his short life to fighting against the illness laid upon him by fate. According to the foundation's website, PolG is characterized by mitochondrial dysfunction, leading to severe physical and cognitive impairments. It’s remarkable how, even during his ordeal, he sought to shine light on the suffering of others dealing with similar conditions.
"He was not only our family member but also our inspiration. His courage and commitment to raise awareness about PolG inspired countless others across the globe," remarked a family spokesperson. Frederik's determination to make his experience meaningful culminated in the foundation's founding back in 2022, amplifying knowledge about PolG and helping to fund research aimed at finding treatments.
The family, lauding his spirit, shared heartfelt tributes emphasizing how Frederik’s life, though tragically brief, was impactful. Grand Duke Henri released a statement saying, “Frederik embodied the spirit of resilience, and his memory will live on through the foundation he established.”
Frederik's death has triggered widespread grief beyond his immediate family. Supporters of the PolG Foundation and those affected by similar conditions are mourning the loss of the young prince who dared to stand against the illness shadowing his life.
The reaction to the prince’s passing is one of shared sorrow steeped in gratitude for what he accomplished, illuminating the struggles faced by many living with chronic health issues. Prominent figures have expressed their condolences on social media, with several highlighting how Frederik’s fight and advocacy would be remembered and continued.
The PolG Foundation is set to carry on Frederik’s legacy, with planned events aimed at increasing awareness and support for those battling mitochondrial diseases. With the unexpected celebrity he brought to the PolG cause, many are hopeful the foundation will have the resources required to forge new paths for treatment.
The news of Frederik’s death highlights the often-overlooked and harsh realities faced by those living with extreme medical conditions. Such narratives often shift conversations within society toward empathy and advocacy, igniting discussions about the need for more extensive research funding and public support for affected families. They remind us not to take health for granted and reflect on the broader impacts of such diseases.
Luxembourg has lost one of its young voices, but through Frederik’s foundation and the stories shared by those he touched, his spirit undoubtedly will remain alive. The hope is to see advancements toward curing PolG and similar conditions, ignited by the young prince's courage and tireless efforts.
The family has requested privacy during this difficult time but noted they appreciate the thoughts and prayers extended from across the world. The legacy of Prince Frederik will undoubtedly echo for years to come through the lives he changed and the awareness he brought to PolG.