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29 January 2025

Enhancing Brain Tumor Classification With Dilated SE-DenseNet

New deep learning model offers significant improvements over existing MRI classification methods.

A novel convolutional neural network (CNN) has been developed to improve the classification of brain tumors from MRI images, utilizing the enhanced DenseNet-121 architecture complemented by dilated convolutional layers and Squeeze-and-Excitation (SE) networks. Published on January 29, 2025, this research offers significant insights for the medical imaging community, particularly as brain tumors remain one of the most challenging forms of cancer.

The model, trained on data from the Kaggle brain tumor dataset, demonstrated remarkable performance, achieving 96.2% accuracy and an F1-score of 0.965, outperforming existing convolution and transformer-based models, including ResNet-101 and VGG-19. These findings highlight the model's capability to address the pressing need for improved diagnostic tools amid the limited availability of medical imaging data.

Brain tumors are notoriously difficult to treat, with five-year survival rates for malignant primary tumors not exceeding 35%. This stark reality necessitates innovations within clinical practices. Modern neuroimaging techniques, particularly MRI, offer invaluable guidance through preoperative diagnosis and treatment planning. Yet, the constraining regulatory environment surrounding patient data does limit the size of available datasets, complicting the task of creating effective machine learning models for tumor classification.

To tackle these challenges, the research proposes leveraging the traditional DenseNet-121 architecture, integrating dilated convolution to expand the model’s receptive field without increasing parameter count. This innovative combination with the SE module, which adaptsively recalibrates channel-wise feature responses, enables the model to focus on the most relevant information for classification tasks.

The incorporation of dilated convolution allows the model to capture broader contextual information, particularly advantageous when identifying tumors of various sizes and locations. Notably, the SE module helps the neural network learn to suppress less important features, greatly improving its performance on challenging medical imaging tasks.

Results from the study reveal the effectiveness of this dual approach. The newly developed architecture not only outperforms heavier models such as VGG-19 and ViT-L/16 but does so with significantly fewer parameters — just over 8 million compared to over 139 million for VGG-19. This efficiency is particularly important for clinical settings where computational resource optimization is key.

These advances signal wide-ranging applications for the model beyond brain tumor analysis, promising potential improvements across various domains of medical imaging. For example, future explorations may include integrating additional patient data alongside imaging, which could personalize diagnostic processes even more effectively.

While the model shows exceptional promise, researchers acknowledge the need for future work to address issues of dataset diversity and class imbalance often present in medical data. Techniques such as Generative Adversarial Networks (GANs) may be employed to generate synthetic images, thereby improving the model’s robustness.

Looking forward, there are plans to extend the architecture to accommodate 3D MRI images, which may significantly improve the accuracy by incorporating volumetric data. This transition necessitates adjustments to both the preprocessing steps and the network architecture itself, allowing for enhanced spatial information capture.

Overall, the successful integration of dilated convolutions and SE modules within the CNN framework marks a significant milestone for medical imaging research. It not only demonstrates the capacity to augment diagnostic accuracy but also sets the stage for adopting similar methodologies across other medical imaging challenges.