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Science
25 February 2025

Cancer Mortality Trends Uncovered Across Northwest China Provinces

Study reveals significant cancer mortality rates and impact on life expectancy from 2013 to 2021.

Cancer mortality continues to be a significant health challenge across six provinces of northwest China, according to new findings from researchers analyzing trends from 2013 to 2021. The study, leveraging data collected through the National Cause-of-Death Surveillance System, sheds light on how these trends affect life expectancy and highlights the necessity for targeted interventions.

The research encompassed the Xinjiang Uyghur Autonomous Region, Qinghai Province, Shaanxi Province, Gansu Province, Ningxia Hui Autonomous Region, and Inner Mongolia Autonomous Region. During this period, the age-standardized cancer mortality rate remained stable overall but exhibited a decrease between 2017 and 2021, at -5.64% annually. "Cancer remains a pressing public health concern in China, where the cancer spectrum is multifaceted," the authors noted. Men consistently outnumbered women in cancer mortality rates, with 178,176 male deaths recorded compared to 102,791 female deaths.

Life expectancy increased by 1.01 years across these provinces from 2013 to 2021, driven partly by changes in cancer mortality trends, which contributed approximately 0.217 years or 21.38% of the overall increase. The greatest benefit was observed among the very young, with the 0-1 year age group recording the most significant difference. The authors stress, “Preventive interventions targeting male groups and the elderly population need to be strengthened.”

Throughout the study timeframe, the total number of cancer deaths climbed from 24,333 to 33,262, with the crude death rate rising from 84.14 per 100,000 to 113.23 per 100,000. Such statistics indicate pressing health demands, particularly for vulnerable demographics like men and the elderly. Researchers highlighted the necessity for nuanced cancer prevention efforts linked to demographic and geographic contexts.

Methodologically, the study utilized Joinpoint software to calculate annual percentage changes and employed Arriaga’s decomposition to assess cancer’s contribution to life expectancy by age group. This comprehensive approach allowed for detailed tracking of mortality trends and years of life lost (YLL), which saw increases from 525,609.6 to 640,313.7 person-years during the studied timeframe.

The findings indicate overwhelming significance for public health policy, particularly as demographic shifts and aging populations exacerbate cancer mortality rates. For the age group 65 years and older, cancer mortality remains high, which suggests the requirement for enhanced preventive strategies aimed at older individuals. Such insights provide valuable data for health officials as they seek to devise effective cancer control measures.

From the statistical analyses of cancer-related deaths across the provinces, Gansu Province registered the highest mortality numbers at 76,615 deaths. Notably, the pattern of mortality rates differed substantially across urban and rural settings, contributing to disparities also seen within the demographic data analyzed. The reduction of mortality rates seen among the female population after 2017 stands as one hopeful aspect against the backdrop of rising male mortality rates.

Despite these promising declines, the burden of disease represented by years of life lost continues to grow, emphasizing the need for targeted health interventions. With the total YLL rate increasing systematically, the call for improved healthcare accessibility and preventative measures grows stronger. The research advocates for future initiatives to focus on behavioral changes among populations at risk, particularly among men who demonstrate persistent unhealthy lifestyle patterns.

Seen as both comprehensive and urgent, the study presents policymakers with clear data trends and actionable insights necessary to combat the rising tide of cancer mortality. Continued public health vigilance, supported by data-driven interventions, remains the key to reducing the impact of cancer across northwest China.