On August 23, 2025, a new dental concern made headlines as dentists across the United States raised alarms about a side effect linked to the widely used diabetes and weight-loss medications Ozempic and Wegovy. The phenomenon, now colloquially dubbed “Ozempic teeth,” is drawing attention from both healthcare professionals and patients, as reports of unexpected oral health issues surface among users of these GLP-1 drugs.
Ozempic and Wegovy, both containing the active ingredient semaglutide, have surged in popularity over the past few years for their effectiveness in managing type 2 diabetes and, more recently, for their ability to aid in weight loss. However, as their use has widened, so too has the spectrum of potential side effects. According to NEXSTAR, dentists are now observing a subset of patients developing dental problems that weren’t previously among the most common side effects listed for these medications. The term “Ozempic teeth” has quickly caught on among both medical professionals and the public to describe this emerging issue.
Adam Taylor, an anatomy professor at Lancaster University, explained in The Conversation that the root of the problem lies in how semaglutide interacts with the body’s salivary glands. “Medications like Ozempic and Wegovy can lead to dry mouth because the active ingredient, semaglutide, affects the salivary glands,” Taylor noted. Saliva plays a crucial role in maintaining oral health, helping to wash away food particles and neutralize acids produced by bacteria. When its production drops, the mouth becomes more susceptible to a host of dental problems.
But there’s another twist. Semaglutide doesn’t just dry out the mouth; it also makes users feel less thirsty. As a result, many people on these medications tend to drink less water throughout the day. This combination—reduced saliva and decreased water intake—creates a perfect storm for oral health issues. “Those factors combined increase the risk of cavities and gum disease,” Dr. Rajpal Anjali, a cosmetic dentist at Beverly Hills Dental Arts, told NEXSTAR.
For some users, the situation is worsened by additional side effects such as acid reflux and vomiting, both of which can erode tooth enamel. “Most users tolerate GLP-1 medications like Ozempic without serious oral health issues, but a subset experience notable side effects such as dry mouth, nausea, or vomiting, which can indirectly affect teeth and gums,” Anjali explained. The acid from reflux or vomit is especially harsh on enamel, wearing it down over time and leaving teeth more vulnerable to decay and sensitivity.
So, what should patients and their dentists be watching for? According to Anjali, the warning signs of “Ozempic teeth” can include increased tooth sensitivity, persistent dry mouth, visible enamel erosion, gum irritation, receding gums, and even slower healing after dental procedures. These issues may not appear immediately but can develop gradually, especially in the first few months after starting the medication.
“Dentists should also be aware of these potential risks and monitor patients accordingly, especially in the first few months after starting the medication,” Anjali added. She emphasized the importance of close communication between patients and their dental care providers. Anyone taking a GLP-1 drug like Ozempic or Wegovy should inform their dentist, particularly if they notice any changes in their oral health. Early intervention can make a significant difference in preventing more severe complications.
One of the most concerning aspects of “Ozempic teeth” is that, unlike some other side effects of GLP-1 medications, the dental damage may not be reversible even if the drug is discontinued. Once enamel is lost or gum tissue recedes, it cannot be fully restored. This reality underscores the need for proactive prevention and regular dental checkups for anyone on these medications.
Preventing “Ozempic teeth” isn’t necessarily complicated, but it does require attention to daily habits. Taylor recommended a straightforward approach: “One simple way to prevent ‘Ozempic teeth’ is to drink more water.” Staying hydrated helps keep saliva flowing, which in turn protects teeth and gums. For those experiencing persistent dry mouth, chewing sugar-free gum can also stimulate saliva production, offering another line of defense against cavities and gum disease.
While the majority of Ozempic and Wegovy users will likely never encounter these dental issues, the warnings from dental professionals are clear: vigilance is key. Routine dental visits, good oral hygiene, and open communication with healthcare providers can go a long way in safeguarding oral health. “Anyone taking a GLP-1 should notify their dentist so they can get extra care for their teeth as needed,” Anjali advised.
The rise of “Ozempic teeth” serves as a reminder that even the most promising new medications can carry unexpected risks. As these drugs become more common, especially among those seeking weight loss, it’s crucial for patients to be informed about all potential side effects—not just the ones that appear on the label. Dentists, too, are being urged to stay alert, particularly in the early months of a patient’s GLP-1 treatment, when oral health changes may first appear.
It’s worth noting that the dental community isn’t sounding the alarm for all users—most people tolerate GLP-1 drugs without major oral health complications. But for that subset who do experience problems, the effects can be significant and long-lasting. As more is learned about “Ozempic teeth,” the hope is that increased awareness will lead to better prevention, early intervention, and ultimately, healthier smiles for all.
As the medical field continues to unravel the full range of effects associated with GLP-1 drugs like Ozempic and Wegovy, patients are encouraged to take a proactive stance. Staying hydrated, practicing diligent oral care, and keeping healthcare providers in the loop are simple but effective steps. In the end, a little extra attention to dental health could make all the difference for those benefiting from these groundbreaking medications.
