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Science
28 November 2025

Study Reveals Brain Maturity Arrives Decades Later Than Thought

Groundbreaking research from Cambridge finds key brain development phases continue until age 32 and beyond, challenging assumptions about when adulthood truly begins.

For decades, the world has treated the age of 18 as the gateway to adulthood. It’s the moment when you can vote, sign contracts, and—in most places—be held fully responsible for your actions. But, as it turns out, your brain might beg to differ. According to a sweeping new study led by the University of Cambridge and published in Nature Communications, the brain’s journey to adulthood is far longer and more complex than anyone previously thought, stretching well into your early thirties and beyond.

The research, which analyzed nearly 4,000 MRI scans from participants aged from infancy to 90 years, has mapped out five distinct “eras” of brain development. These eras are separated by four major turning points, occurring at approximately ages 9, 32, 66, and 83. The findings, reported by BBC News, Al Jazeera, and Earth.com, are already shaking up long-held assumptions about how—and when—our brains mature.

“We know the brain’s wiring is crucial to our development, but we lack a big picture of how it changes across our lives and why,” said Dr. Alexa Mousley, Gates Cambridge Scholar and lead researcher. Her team’s work is the first to identify major phases of brain wiring across the human lifespan, offering a new lens through which to view everything from learning to aging, and even mental health.

The Five Eras of Brain Development

The study’s most headline-grabbing revelation is the extension of adolescence, which now appears to last until the age of 32. That’s a far cry from the traditional view, which pegged the end of adolescence somewhere in the late teens or early twenties. In fact, as Al Jazeera highlighted, the researchers found that “adolescent topological development extends to around 32 years old, before brain networks begin a new trajectory of topological development.”

Let’s break down these eras:

1. Childhood (Birth to 9 years): In the earliest years, the brain experiences a whirlwind of growth. Babies start with a surplus of synapses—the connections between neurons. Over time, the brain prunes away the weaker connections, keeping only the strongest. Grey and white matter grow rapidly, cortical thickness peaks, and the brain’s folds settle into their characteristic patterns. As Earth.com explains, “network consolidation” is the name of the game, though the overall efficiency of the brain’s wiring actually dips temporarily as this reorganization takes place.

2. Adolescence (9 to 32 years): This era is a marathon, not a sprint. White matter continues to grow, and communication across brain networks becomes more efficient. Cognitive abilities improve, but this is also the period when many mental health disorders tend to surface. According to the study, “the adolescent era is the only one in which this efficiency is increasing.” Puberty may mark the start of adolescence, but the end is far murkier—scientifically speaking, it doesn’t arrive until the early thirties. “While puberty offers a clear start, the end of adolescence is much harder to pin down scientifically. Based purely on neural architecture, we found that adolescent-like changes in brain structure end around the early thirties,” said Dr. Mousley.

3. Adulthood (32 to 66 years): Hitting 32 isn’t just about getting a few more wrinkles or graying hairs. Around this age, the brain enters what researchers call “adult mode.” Neural architecture stabilizes, and brain regions become more compartmentalized. This phase, the longest of all, is marked by a plateau in intelligence and personality traits. Life events, such as parenthood, may nudge some structural changes, but the overall landscape is much steadier than in earlier years.

4. Early Ageing (66 to 83 years): The mid-sixties usher in a gradual decline in brain connectivity, driven by the degeneration of white matter. Cognitive flexibility and processing speed may wane, and the risk of conditions like hypertension and dementia increases. Still, as Dr. Mousley noted, “the data suggest that a gradual reorganisation of brain networks culminates in the mid-sixties.”

5. Late Ageing (83 years and above): The final era sees further reductions in global connectivity, with the brain increasingly relying on localized regions. According to the study’s authors, this may “reflect a true weakening relationship between age and structural brain topology in late life.” There’s less data for this age group, but the pattern is clear: the brain’s wiring becomes more specialized as overall connectivity drops.

Why These Findings Matter

The study’s implications are far-reaching. For one, it challenges the notion that brain development is smooth and linear. Instead, as Professor Duncan Astle of Cambridge University put it, “Looking back, many of us feel our lives have been characterised by different phases. It turns out that brains also go through these eras.” These turning points could help explain why some children struggle in school, why mental health issues often emerge in adolescence, and why memory loss or dementia become more common in later life.

The research also sheds light on the brain’s vulnerabilities. By pinpointing when the brain is most susceptible to disruption—whether from disease, mental health disorders, or lifestyle factors—scientists hope to develop better interventions. “Understanding that the brain’s structural journey is not a question of steady progression, but rather one of a few major turning points, will help us identify when and how its wiring is vulnerable to disruption,” Professor Astle told Earth.com.

Challenging Old Assumptions

Traditionally, adolescence was thought to end at 19, as per the World Health Organization, or perhaps in the early twenties, according to a 2018 report in The Lancet. But this new research, as reported by BBC News and Al Jazeera, pushes the boundary much further. The study’s authors even caution that the transition to adulthood is influenced by cultural, historical, and social factors, making it context-dependent rather than purely biological. For now, the findings apply most directly to Western countries, where the data was collected.

These revelations have already made their way into public consciousness. BBC News featured the brain’s new “age of adulthood” as a key question in its weekly news quiz, underscoring the story’s broad appeal and significance.

The Road Ahead

As tools for studying the brain grow more sophisticated, researchers hope to refine this timeline even further. For now, the five-era framework offers a powerful new way to understand the human brain’s lifelong transformation. It reminds us that while legal and social definitions of adulthood may be fixed, our brains are still works in progress—sometimes well into the years when we’re expected to have it all figured out.

For anyone who’s ever felt like they were still “growing up” in their twenties or even early thirties, science now has your back. Turns out, your brain was, too.